Jiaqi Li^1,*, Chenglong Zhu^1,*, Yan Liao^1,*, Xuan Yin^1,*, Rui Zhao² , Changli Wang³, Doblin Sandai⁴, Haoling Zhang⁴ , Wangzheqi Zhang¹

¹School of Anesthesiology, Naval Medical University, Shanghai 200433, China. 

²Gansu University of Chinese Medicine, No. 35 Dingxi East Road, Lanzhou 730000, Gansu, China. 

³Department of Anesthesiology, Changhai Hospital, Naval Medical University, Shanghai 200433, China. 

⁴Department of Biomedical Sciences, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang 13200, Malaysia. 

^*The authors contribute equally.

Address correspondence to: Doblin Sandai, Department of Biomedical Sciences, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang 13200, Malaysia. E-mail: doblin@usm.my. Haoling Zhang, Department of Biomedical Sciences, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang 13200, Malaysia. E-mail: zhanghaolingedu@163.com. Wangzheqi Zhang, School of Anesthesiology, Naval Medical University, 800 Xiangyin Road, Yangpu District, Shanghai 200433, China. E-mail: zwzq001031@smmu.edu.cn.

DOI: https://doi.org/10.61189/775612vwvmhm

Received October 3, 2025; Accepted February 28, 2026; Published March 31, 2026

Wangzheqi Zhang¹, Chenglong Zhu¹, Xingzhi Liao², Feixiang Wu³, Hui Chen⁴, Wenyun Xu⁵, Jinlong Qu⁶, Miao Zhou⁷, Jinfei Shi⁸, Liangqing Lin⁹, Shengyun Cai¹⁰, Wenchao Gao¹¹, Hua Tang¹², Ying Huang¹³, Zui Zou¹

¹School of Anesthesiology, Naval Medical University, Shanghai 200433, China. ²Department of Anesthesiology, 904th Hospital of The Joint Logistics Support Force of the PLA, Wuxi 214044, Jiangsu, China. ³Department of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China. ⁴Department of Anesthesiology and Perioperative medicine, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai 200434, China. ⁵Department of Anesthesiology, Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China. ⁶Department of Emergency and Critical Care Medicine, Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China. ⁷Department of Anesthesiology, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing Medical University, Nanjing 210009, Jiangsu, China. ⁸Department of Anesthesiology, Anhui Provincial Hospital of the Armed Police, Hefei 230001, China. ⁹Department of Anesthesiology, The First Hospital of Putian City, Teaching Hospital of Fujian Medical University, Putian 351100, Fujian, China. ¹⁰Department of Obstetrics and Gynecology, First Affiliated Hospital of Naval Medical University, Shanghai 200433, China. ¹¹Department of Colorectal Surgery, Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China. ¹²Department of Thoracic Surgery, The Second Affiliated Hospital of Naval University, Shanghai 200003, China. ¹³Department of Intensive Care Unit, The Affiliated Huaian No.1 People’s Hospital of Nanjing Medical University, Huaian, Jiangsu 223300, China. 

Address correspondence to: Hua Tang, Department of Thoracic Surgery, The Second Affiliated Hospital of Naval University, Shanghai 200003, China. Email: Tangh_mits@163.com. Ying Huang, Department of Intensive Care Unit, The Affiliated Huaian No.1 People’s Hospital of Nanjing Medical University, Huaian, Jiangsu 223300, China. Email: huangying5249@163.com. Zui Zou, School of Anesthesiology, Naval Medical University, 168 Changhai Road, Shanghai 200433, China. Email: zou-zui@smmu.edu.cn.

Acknowledgement: This study was funded by the following projects: Shanghai Industrial Collaborative Innovation Project (HCXBCY - 2023 – 041, XTCX - KJ - 2024 - 39, HCXBCY - 2024 – 033), 2024 Basic Medicine Innovation Open Topic (JCKFKT - MS - 002), and the 2024 Annual Pharmaceutical Science and Technology Key Research Project of the China Medicine Education Association (2024KTZ011).

DOI: https://doi.org/10.61189/447393ljoyfh

Received January 20, 2025; Accepted February 20, 2025; Published March 31, 2025

Kai Wang¹, Zhe Zhang¹, Mingling Wang², Shiming Feng³, Huanjia Xue¹, Xiang Huan¹, Liwei Wang¹ 

¹Department of Anesthesiology, ²Operating Room, ³Department of Orthopaedics, Xuzhou Clinical College Affiliated  to Xuzhou Medical University, Xuzhou 221009, Jiangsu, China. 

Address correspondence to: Liwei Wang, Department of Anesthesiology, Xuzhou Central Hospital, No.199 Jiefang South Road, Quanshan District, Xuzhou 221009, Jiangsu, China. Email: 760020230115@xzhmu.edu.cn.

Acknowledgement: This work was supported by Young Scientist Fund of National Natural Science Foundation of  China (81700078) and Xuzhou Medical Key Talents program (XWRCHT20220051). 

DOI: https://doi.org/10.61189/143336qedqgl

Received November 2, 2024; Accepted February 14, 2025; Published March 31, 2025

Highlights

● Training with the multi-objective teaching model significantly improved in perioperative skills of residents. 

● Multi-objective teaching model effectively facilitates the acquisition of comprehensive theoretical knowledge in anesthesiology. 

● Multi-objective teaching model emphasizes the development of teamwork skills.

Kecheng Zhai^1,2, Yangmengna Gao^1,2, Yu Xiang^1,2, Jiameng Liu^1,2, Shangping Fang^1,2

¹School of Anesthesiology, ²Anesthesia Laboratory and Training Center, Wannan Medical College, Wuhu 241002,  Anhui Province, China.

Address correspondence to: Shangping Fang, Anesthesia Laboratory and Training Center, Wannan  Medical College, No. 22, Wenchang West Road, Higher Education Park, Wuhu 241002, Anhui Province, China. E-mail: 20180041@wnmc.edu.cn.

Acknowledgement: This work was supported by the National College Student Innovation and Entrepreneurship Project (202310368016) and Anhui Province College Student Innovation and Entrepreneurship Project  (S202310368027).

DOI: https://doi.org/10.61189/619896szhnms

Received October 24, 2024; Accepted January 8, 2025; Published March 31, 2025

Highlights

● Mitochondrial autophagy is essential for maintaining mitochondrial health by selectively degrading damaged mitochondria. This process involves two main pathways: ubiquitin-dependent and ubiquitin-independent autophagy. 

● Sepsis causes organ dysfunction due to infection, with acute lung injury (ALI) being a common secondary condition. ALI is characterized by excessive inflammation in the lungs, leading to mitochondrial dysfunction. 

● Understanding the mechanisms of mitochondrial autophagy can provide new insights for treating sepsis-associated ALI. Continued research could identify novel therapeutic targets to improve outcomes for patients with ALI and sepsis. 

● In the early stages of sepsis-related ALI, mitochondrial autophagy is enhanced. In severe or prolonged cases, excessive mitochondrial autophagy may occur. In the later stages, particularly in severe or chronic cases, mitochondrial autophagy may be impaired or completely lost. 

● Mitochondrial autophagy holds therapeutic potential for the perioperative assessment and management of sepsis-related ALI. Further investigation into this potential is warranted.

Chenglong Zhu¹, Jianhua Xia², Zui Zou¹

¹School of Anesthesiology, Naval Medical University, Shanghai 200433, China. ²Department of Anesthesiology, Shanghai Pudong New Area People's Hospital, Shanghai 201200, China.

Address correspondence to: Zui Zou, School of Anesthesiology, Naval Medical University, 168 Changhai Road, Yangpu District, Shanghai 200433, China. E-mail: zouzui@smmu.edu.cn.

DOI: https://doi.org/10.61189/905466eqluyw

Received October 26, 2024; Accepted January 7, 2025; Published June 30, 2025

Difficult airways are a common concern for physicians in the department of anesthesiology, emergency medicine, and critical care medicine. SEEK^flex (Safe Easy Endotracheal kit-flexible) is a novel multifunctional introducer developed by our team to address difficult airways.  It has been registered as a medical device in  China (Zhejiang Medical Device Registration  Approval No. 20232081322).

The SEEK^flex system features a dual-component  design, consisting of a primary introducer and a  supplementary adapter. With an outer diameter of 4.0 mm and an inner diameter of 2.4 mm, it is compatible with tracheal tubes of an internal  diameter exceeding 4.5 mm. The introducer, extending from 43 to 81 cm, is equipped with  a flexible steel core for guidance and a smooth  polyvinyl chloride (PVC) sheath. This assembly  can be securely fastened using a blue locking mechanism, as depicted in Figure 1A-B [1]. 

SEEK^flex can be bent at an appropriate angle  due to the malleability of its inner core, allowing it to be easily inserted into the trachea just under the epiglottis in cases of unpredicted  difficult airway (Cormack-Lehane Grade III). This procedure is facilitated by a video laryngoscope. The endotracheal position of SEEK^flex is confirmed by connecting it to an EtCO₂ monitor via the adapter after removing the inner core (Figure 1C). The endotracheal tube can be easily advanced into the trachea using the Seldinger technique, with the guidance of reconnected, post-stretching SEEK^flex. In addition, we have  developed a "12-step" approach for awake  tracheal intubation using SEEK^flex and a video laryngoscope, which has yielded satisfactory clinical results [2].

At the distal end of the outer catheter, there is one vent at the top and 4 rows of lateral vents. After removing the inner core and attaching the adapter, local anesthetic can be administrated, and oxygenation can be maintained using a ventilator, like a slender tracheal tube. The original version of this introducer was used for reintubation of COVID-19 patients, and the outer catheter could be left in place for subglottic oxygenation after extubation [3]. This feature is also used for oxygenation maintenance and tracheal intubation in emergency situations during  bronchoscopic balloon dilation [4]. 

Several randomized controlled studies, approved by the Ethics Committee of the Naval Medical University and currently in the process of data collection, may further provide robust evidence of its safety and efficacy. We believe that this new multifunctional introducer can be widely adopted by anesthesiologists due to its versatility across multiple clinical scenarios.

Tian Zhou¹, Chenglong Zhu¹, Feixiang Wu², Xingzhi Liao³, Wenyun Xu⁴, Hui Chen⁵, Jinlong Qu⁶, Jinfei Shi⁷, Yaohua Yu⁸, Ying Huang⁹, Miao Zhou¹⁰, Hua Tang¹¹, Shengyun Cai¹², Wenchao Gao¹³, Zui Zou¹

¹School of Anesthesiology, Naval Medical University, Shanghai, 200433, China. ²Department of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China. ³Department of Anesthesiology, The 904th Hospital of the Logistics Support Force of the Chinese People's Liberation Army, Wuxi 214044, Jiangsu Province, China. ⁴Department of Anesthesiology, Shanghai Changzheng Hospital, Naval Medical University, Shanghai, 200003, China. ⁵Department of Anesthesiology and Perioperative medicine, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai 200434, China. ⁶Department of Emergency and Critical Care Medicine, Shanghai Changzheng Hospital, Naval Medical University, Shanghai 200003, China. ⁷Department of Anesthesiology, Anhui Provincial Hospital of the Armed Police, Hefei 230001, Anhui Province, China. ⁸Department of Anesthesiology, The First Hospital of Putian City, Putian 351100, Fujian Province, China. ⁹Department of Intensive Care Unit, the Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University, Huai'an 223300, Jiangsu Province, China. ¹⁰Department of Anesthesiology, the Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing Medical University, Nanjing 210009, Jiangsu Province, China. ¹¹Department of Thoracic Surgery, Shanghai Changzheng Hospital, Naval Medical University, Shanghai 200003, China. ¹²Department of Obstetrics and Gynecology, The First Affiliated Hospital of Naval Medical University, Shanghai 200433, China. ¹³Department of Colorectal Surgery, Shanghai Changzheng Hospital, Naval Medical University, Shanghai 200003, China.

Address correspondence to: Shengyun Cai, Department of Obstetrics and Gynecology, First Affiliated Hospital of Naval Medical University, 168 Changhai Road, Shanghai 200433, China. Email: caicai24@126.com. Wenchao Gao, Department of Colorectal Surgery, Second Affiliated Hospital of Naval Medical University, 415 Fengyang Road, Shanghai 200003, China. Email: gaowenchao2007@163.com. Zui Zou, School of Anesthesiology, Naval Medical University, 168 Changhai Road, Shanghai 200433, China. Email: zouzui@smmu.edu.cn.

Acknowledgement: This study was funded by the following projects: Shanghai Industrial Collaborative Innovation Project (HCXBCY - 2023 – 041, XTCX - KJ - 2024 - 39, HCXBCY - 2024 – 033), 2024 Basic Medicine Innovation Open Topic (JCKFKT - MS - 002), and the 2024 Annual Pharmaceutical Science and Technology Key Research Project of the China Medicine Education Association (2024KTZ011).

DOI: https://doi.org/10.61189/707615erclry

Received February 20, 2025; Accepted February 24, 2025; Published June 30, 2025

Chong Zhou^1,2, Xiaoqi Li², Menglan Hao^1,3, Shuqing Chang^1,2, Jinjing Xia^1,2,3

¹University of Shanghai for Science and Technology, Shanghai 200093, China. 

²Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China. 

³Shanghai Jiao Tong University, Shanghai 200030, China.

Address correspondence to: Jinjing Xia, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, No. 241 Huaihai West Road, Xuhui District, Shanghai 200030, China. E-mail: xjj1099@shchest.org.

DOI: https://doi.org/10.61189/898430njufld

Received October 27, 2025; Accepted December 4, 2025; Published March 31, 2026

Mingling Wang¹, Lien Qi¹, Kai Wang², Jing Zhang³, Xiaoyan Wang¹

Departments of ¹Operating Room, ²Anesthesiology, ³Nursing, Xuzhou Central Hospital, Xuzhou 221009, Jiangsu Province, China.

Address correspondence to: Xiaoyan Wang, Department of Operating Room, Xuzhou Central Hospital, Jiefang South Road, No. 199, Xuzhou 221009, Jiangsu Province, China. Tel: +86-15351687352; E-mail: 531446635@qq.com; Jing Zhang, Department of Nursing, Xuzhou Central Hospital, Jiefang South Road, No. 199, Xuzhou 221009, Jiangsu Province, China. Tel: +86-18012018586; E-mail: 2038634928@qq.com.

Ethics approval and consent to participate: The study protocol was approved by the Institutional Review Committee of Xuzhou Central Hospital (approval no. XZXY-LK-20220114-027) and conducted in accordance with the ethical principles for medical research involving human subjects described in the Declaration of Helsinki. Prior to inclusion in this study, informed consent was obtained from all participants. Trial Registration clinicaltrials.gov Identifier: CTR20200708.

DOI: https://doi.org/10.61189/082747tokokd

Received July 8, 2024; Accepted September 3, 2024; Published June 30, 2025

Highlights

● Gastrointestinal decompression (GID) near the gastric body reduces nausea, vomiting, and discomfort.

● GID near the gastric body is conducive to exposure of the operative space.

● GID near the gastric body improves postoperative recovery of gastrointestinal function.

Wenxin Shi, Yajun Hu, Jin Lan, Jun Xiong, Zhiyong Li

Department of Pathology, Faculty of Medical Imaging, Naval Medical University, Shanghai 200082, China.

Address correspondence to: Jun Xiong, Department of Pathology, Faculty of Medical Imaging, Naval Medical University, Xiangyin Road, Yangpu District, Shanghai 200082, China. E-mail: xiongjun2001@163.com; Zhiyong Li, Department of Pathology, Faculty of Medical Imaging, Naval Medical University, Xiangyin Road, Yangpu District, Shanghai 200082, China. E-mail: zhiyongli@smmu.edu.cn.

Acknowledgement: This work was supported by grants from the Shanghai Science (23ZR1477400) and Technology Commission Project (201409004600).

DOI: https://doi.org/10.61189/629158xrbqam

Received October 28, 2024; Accepted January 7, 2025; Published June 30, 2025

Highlights

● Intestinal barrier dysfunction increases the risk of perioperative complications.

● The immunologic barrier is crucial for maintaining intestinal homeostasis.

● Perioperative factors compromise the intestinal immunologic barrier, increasing infection risk.

● An imbalance between intestinal microbiota and immune cells affects postoperative recovery.

● Clinical intervention studies targeting the intestinal barrier are summarized.

Dezhi Guo^1,*, Jingjing Lu^2,*, Limin Wei³, Wenyi Wang⁴

¹Department of Anesthesiology, The First Naval Hospital of Southern Theater Command, Zhanjiang 524005, Guangdong, China. 

²Clinical College of Traditional Chinese Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu, China. 

³Liaocheng People's Hospital, Liaocheng 252000, Shandong, China. 

⁴Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan. 

^*The authors contribute equally.

Address correspondence to: Limin Wei, Liao cheng People's Hospital, No. 67 Dongchang West Road, Dongchangfu District, Liaocheng 252000, Shandong, China. E-mail: weilimin19860914@163.com. Wenyi Wang, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan. E-mail: w.wang.mk@juntendo.ac.jp.

DOI: https://doi.org/10.61189/056184yqnaiu

Received December 10, 2025; Accepted February 28, 2026; Published March 31, 2026

Ruilong Li^1,2*, Dezhi Guo^1,2*, Tianying Li^1,2, Panpan Hu^1,3, Tianying Xu¹

¹Department of Anesthetic Pharmacology, School of Anesthesiology, Second Military Medical University/Naval Medical University, Shanghai 200433, China. ²College of Basic Medicine, Second Military Medical University/Naval Medical University, Shanghai 200433, China. ³National Key Laboratory of Immunity & Inflammation, Second Military Medical University/Naval Medical University, Shanghai 200433, China. 

* The authors contribute equally.

Address correspondence to: Tianying Xu, Department of Anesthetic Pharmacology, School of Anesthesiology, Second Military Medical University/Naval Medical University, 800 Xiangyin Road, Shanghai 200433, China. Tel: +86 021 81872029, E-mail: xutianying@smmu.edu.cn; Panpan Hu, Department of Anesthetic Pharmacology, School of Anesthesiology, National Key Laboratory of Immunity & Inflammation, Second Military Medical University/Naval Medical University, 800 Xiangyin Road, Shanghai  200433, China. Tel: +86 021 81872029, E-mail: hpp510@smmu.edu.cn.

Acknowledgement: This work was supported by the Basic Medical Research Fund of Naval Medical University (2023QN034). The authors would like to thank all the guest editors and anonymous reviewers for their constructive comments.

DOI: https://doi.org/10.61189/313377zqjuff

Received January 23, 2024; Accepted April 29, 2024; Published September 30, 2024

Highlights

● Patients with heatstroke often suffer from multiple organ dysfunction and have a high fatality rate. 

● The molecular mechanisms underlying multiple organ damage in heatstroke are complex. 

● This review outlines the manifestations of multiple organ dysfunction caused by heatstroke and explores the possible molecular mechanisms involved.

Ziwei Xia^1,2, Guangkuo Ma^1,2, Huanjia Xue^1,2, Hui Wu^1,2, Liwei Wang^1,2, Kai Wang^1,2

¹Graduate School, Xuzhou Medical University, Xuzhou 221009, Jiangsu Province, China. ²Department of Anesthesiology, Xuzhou Central Hospital, Xuzhou 221009, Jiangsu Province, China.

Address correspondence to: Kai Wang, Department of Anesthesiology, Xuzhou Central Hospital, No. 199 Jiefang South Road, Quanshan District, Xuzhou 221009, Jiangsu Province, China. Tel: +86-18112012729; E-mail: wangkaistream99@sina.com or 760020230115@xzhmu.edu.cn.

Acknowledgement: This work was supported by the Department of Anesthesiology of Xuzhou Central Hospital. The authors would like to thank all the guest editors and anonymous reviewers for their constructive comments.

DOI: https://doi.org/10.61189/768941essmpc

Received January 25, 2024; Accepted April 2, 2024; Published September 30, 2024

Highlights

● In the realm of forearm, wrist, and hand surgeries, ultrasound-guided forearm selective nerve block techniques offer distinct advantages over alternative methods such as Bier's block, brachial plexus block, and wrist block. These advantages include reduced anesthesia-related time, prolonged duration of analgesia, and minimal inter-ference with upper extremity motor function. 

● Ultrasound-guided forearm selective nerve block stands as a straightforward and conducive anesthesia method ideally suited for distal upper limb surgeries. This approach harmonizes seamlessly with the principles of fast surgical recovery and enhances patient comfort during both diagnostic and therapeutic procedures. 

● Supplementation of dexmedetomidine or dexamethasone in ultrasound-guided selective nerve blocks of the forearm has been shown to significantly prolong the duration of analgesia.

Mingling Wang^1*, Gaolei Jia^2*, Kai Wang³, Haifeng Zhuang⁴, Li Ma², Ping Wang⁴ 

¹Department of Operating Room, Xuzhou Central Hospital, Xuzhou 221009, China. ²Department of Thyroid, Xuzhou Central Hospital, Xuzhou 221009, China. ³Department of Anesthesiology, Xuzhou Central Hospital, Xuzhou 221009, China. ⁴Department of Nursing, Xuzhou Central Hospital, Xuzhou 221009, China. 

*The authors contribute equally.

Address correspondence to: Ping Wang, Department of Nursing, Xuzhou Central Hospital, No. 199 Jiefang South Road, Xuzhou 221009, China. Tel: +86-18952172176; Fax: 0086-0516-83956203;  E-mail: wangkaistream99@xzhmu.edu.cn. Li Ma, Department of Thyroid, Xuzhou Central Hospital, No. 199 Jiefang South Road, Xuzhou 221009, China. Tel: +86-18112023690; E-mail: 675694863@ qq.com.

Acknowledgement: This study was financially supported by a grant from the Xuzhou City Science and Technology Project (KC22156). We thank International Science Editing (http://www.internationalscienceediting.com) for editing this manuscript.

DOI: https://doi.org/10.61189/031494xruanc

Received May 17, 2024; Accepted August 9, 2024; Published September 30, 2024

Highlights

● A novel modified retracting arm for transaxillary endoscopic thyroid surgery was designed. 

● The modified hook better exposed and protected the recurrent laryngeal nerve and parathyroid glands.

● The modified retracting arm achieved better visual analog scale and cosmetic scores.

Yan Liao^1*, Zhanheng Chen^1*,Wangzheqi Zhang^1*, Lindong Cheng² , Yanchen Lin² , Ping Li³ , Miao Zhou⁴ ,  Mi Li¹ , ChunHua Liao¹ 

¹School of Anesthesiology, Naval Medical University, Shanghai 200433, China. ²Graduate School, Hebei North University, Zhangjiakou 075000, China. ³Graduate School, Wannan Medical College, Wuhu 241000, China. ⁴Department of Anesthesiology, the Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing Medical University, Nanjing 210009, China. 

* The authors contribute equally.

Address correspondence to: Miao Zhou, The Affiliated Cancer Hospital of Nanjing Medical University, Department of Anesthesiology, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing Medical University, Nanjing 210009, China. E-mail: zhoumiao2613@163.com; Tel: +86  18217567295. Mi Li, School of Anesthesiology, Naval Medical University, 800 Xiangyin Road, Yangpu District, Shanghai 200433, China. E-mail: limi@smmu.edu.cn; Tel: +86-21-81872033. Chunhua Liao, School of Anesthesiology, Naval Medical University, 800 Xiangyin Road, Yangpu District. Shanghai  200433, China. E-mail: Liaochh7@smmu.edu.cn; Tel: +86 21 81872025.

Acknowledgement: This work was supported by the National Natural Science Foundation of China under Grants 62002297, 62073225, and 61836005, the Science and Technology Commission of Shanghai Municipality under Grant 20XD1434400, talent Development Fund of Shanghai under Grant 2020075, Medical-Engineering Cross Fund of Shanghai Jiao Tong University under Grant YG2022QN043, and the Guangxi Science and Technology Base and Talent Special Project under Grant 2021AC19394. The authors would like to thank all the guest editors and anonymous reviewers for their constructive advice.

DOI: https://doi.org/10.61189/275419wdddvs

Received February 21, 2024; Accepted March 25, 2024; Published September 30, 2024

Highlights

● Artificial intelligence (AI) is lauded for its capacity to resolve intricate problems with unwavering efficiency, devoid of fatigue. To elucidate the potential of AI in perioperative pain management, we have meticulously surveyed a vast array of scholarly works to discern the landscape of research in this multifaceted domain. 

● Conventional perioperative pain studies have primarily confined their scope to clinical aspects. However, this review delves into the amalgamation of AI and perioperative pain, heralding a diverse methodology for pain control. 

● AI's applicability in medical domains, particularly anesthesia, has spawned numerous inquiries into its synergy  with perioperative pain. Yet, a dearth of comprehensive reviews encapsulating the current research milieu, pin  pointing hurdles, and envisioning future directions in this sphere necessitated the present discourse. 

● We herein offer horizontal and vertical assessments of diverse models and algorithms employed in periopera  tive pain management, encapsulated in diagrammatic form for reader accessibility. The compilation of this review draws from a spectrum of online scholarly repositories, thus ensuring a thorough and relevant assembly of insights.

Yichun Shen¹, Shuyi Wang¹, Yuhan Shen¹, Hua Xing²

¹School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China. ²Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai 200080, China.

Address correspondence to: Shuyi Wang, School of Health Science and Engineering, University of Shanghai for Science and Technology, NO.516, Jungong Road, Shanghai 200093, China. E-mail: wangshuyi@usst.edu.cn.

DOI: https://doi.org/10.61189/721472czacxf

Received April 12, 2024; Accepted July 11, 2024; Published September 30, 2024

Highlights

● Machine learning can enhance the individualization of treatment in Chinese massage.

● An intelligent system improves the efficiency of Traditional Chinese Medicine massage therapy.

● The integration of Traditional Chinese Medicine Massage Therapy with machine learning represents a new trend in future healthcare.

Yibin Zhang¹, Yan Wang¹, Hongliu Yu²¹School of Medical Devices, Shanghai University of Medicine and Health Sciences, Shanghai 201318, China. ²School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.

Address correspondence to: Hongliu Yu, School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai city Jungong road 516, Shanghai 200093, China. E-mail: yhl98@hotmail.com.

DOI：https://doi.org/10.61189/961030gznunx

Received June 21, 2024; Accepted November 20, 2024; Published December 31, 2024

Highlights

● In prosthetics, using AI algorithms to identify the fused sensor data as known walking patterns has extremely strong expandability. Moreover, as the learning data continues to expand, the robustness of the model itself also increases accordingly.● There are numerous AI algorithms currently available. The effective utilization of algorithm combination techniques to learn from each other’s strengths can significantly improve the accuracy of identification. The combined model of convolutional neural networks (CNN) and bidirectional long short term memory (LSTM) attempted in this paper has witnessed a significant improvement in its comprehensive recognition rate.● In the practical application of prosthetics, the real-time performance during the mode switching transition period is particularly important as it can reflect the flexibility of the prosthetics. In this paper, the algorithm optimized by the AI model has controlled the delay rate within one gait cycle, greatly enhancing the safety and reliability of pro-sthetics in actual use.

Xiaolei Cai^1*, Qi Sun^2*, Cen Qiu^2*, Zhenyu Xie¹, Jiahao He², Mengting Tu³, Xinran Zhang², Yang Liu², Zhaojun Tan², Yutong Xie², Xixuan He¹, Yujing Ren¹, Chunhong Xue¹, Siqi Wang², Linrong Yuan², Miao Yu², Xuelin Cheng⁴, Xiaopan Li⁴, Sunfang Jiang⁴, Huirong Zhu¹

¹Tangqiao Community Health Service Center, Shanghai 200127, China. ²Shanghai University of Medicine and Health Sciences, Shanghai 201318, China. ³Shanghai DianJi University, Shanghai 201306, China. ⁴Health Man-agement Center, Zhongshan Hospital Affiliated to Fudan University, Shanghai 200032, China.*The authors contribute equally.

Address correspondence to: Sunfang Jiang, Health Management Center, Zhongshan Hospital Affiliated to Fudan University, Gate 5 East Campus, No. 179 Fenglin Road, Xuhui District, Shanghai 200032, China. Email: jiang.sunfang@zs-hospital.sh.cn. Huirong Zhu, Tangqiao Community Health Service Center, No.131 Pujian Road, Pudong New District, Shanghai 200127, China. Email: rachel1022@126.com.

DOI: https://doi.org/10.61189/568091unpkqk

Received May 11, 2024; Accepted July 16, 2024; Published September 30, 2024

Highlights

●This study collected three years of physical examination data from older adults in the Tangqiao community of Shanghai, which is more regionally representative.

●The most suitable model for this study was selected from six machine learning models to construct a fatty liver risk prediction model for the elderly.

●This study combines six feature selection algorithms with varying performance to screen the features most rele vant to fatty liver.

Mengying Zhan, Jiahao Zhang, Yuqiu Zhou, Qijun Xie, Fangfang Luo, Yu Zhou 

School of Health Sciences and Engineering, University of Shanghai for Science and Technology, Shanghai  200093, China. 

Address correspondence to: Yu Zhou, School of Health Sciences and Engineering, University of  Shanghai for Science and Technology, No.516 Jungong Road, Shanghai 200093, China. Tel: +86- 18021042556. E-mail: zhouyu@usst.edu.cn.

DOI: https://doi.org/10.61189/650204jodubt 

Received January 29, 2024; Accepted March 25, 2024; Published September 30, 2024

Highlights

● The effect of electrode-tissue contact force on the efficacy and safety of ablation of atrial fibrillation was reviewed  in detail.

● The existing contact force sensing catheters on the market are compared and introduced.

● Three impedance-related methods for assessing catheter adherence are introduced.

Zhaoyang Yan^1*, Chunhui Qin^2*, Shuya Wang^1*, Zhaohui Xie³, Liyun Kong⁴, Lili Zhong⁵, Hong Wang⁵, Yun Cai⁶, Guohua Jiao⁷, Zhenwei Wang⁸, Qiwen Zhu^9*, Ruoyu Tang^10* 

¹Shanghai Reacool Medical Technology Co., Ltd., Shanghai 200041, China. ²Department of Anesthesiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China. ³Department of Pain Management, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China. ⁴Department of Pain Management, The First Affiliated Hospital of Gan nan Medical University, Ganzhou 341000, Jiangxi Province, China. ⁵Department of Anesthesiology and Pain Man agement, Wuhu Fifth People’s Hospital (Anhui Province Wannan Rehabilitation Hospital), Wuhu 241004, Anhui Province, China. ⁶School of Health and Rehabilitation, Nanjing University of Chinese Medicine, Nanjing 210046, Jiangsu Province, China. ⁷Department of Pain Management, Tongxiang Hospital of Traditional Chinese Medicine, Tongxiang 314500, Zhejiang Province, China. ⁸Department of Respiratory Medicine, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China. ⁹Department of Engineering and Computer Science, Syracuse University, New York State/Syra cuse 13210, the United States of America. ¹⁰Department of Psychology, University of British Columbia (UBC), Van couver V6T 1Z4, British Columbia, Canada. 

 *The authors contribute equally.

Address correspondence to: Lili Zhong, Department of Anesthesiology and Pain Management, No. 2, Zhe-Shan East Road, Jinghu District, Wuhu 241004, Anhui Province, China. Tel: +86-180-0963-7377. E-mail: williyia@wnmc.edu.cn. Zhenwei Wang, Department of Respiratory Medicine, No. 110, Ganhe Road, Hongkou District, Shanghai 200437, China. Tel: +86-189-1875-7762. E-mail: wangzhenwei@ shyueyanghospital.com.

Acknowledgement: This project was supported by the research on the application of digital therapy in the treat ment of neuropathic pain caused by herpes zoster (2023yf004) and the Gansu Province Intelligent Pain Diagnosis and Treatment Industry Technology Center. The authors would like to thank all the guest editors and anonymous reviewers for their constructive advice.

DOI: https://doi.org/10.61189/285507yclyaz

Received June 21, 2024; Accepted September 3, 2024; Published December 31, 2024 

Highlights 

 ● Analysis of collected data reveals that digital therapy offer new treatment methods and options in the field of pain management. After conducting research and analysis, it has been found that digital therapeutics offer new treatment methods and options, especially in the area of perioperative pain management. 

 ● Multiple clinical studies indicate that digital therapy has significant effects in the treatment and relief of pain caused by various conditions. 

 ● Domestic and international policies have positively influenced the development and progress of digital therapy. 

 ● Ethical considerations require continuous evaluation, decision-making, and regulation, warranting ongoing reflection. 

 ● Digital therapeutics, as an emerging intervention for pain, are propelling perioperative pain treatment towards a diversified and personalized comprehensive diagnostic and treatment model.

Weiwei Fan, Lin Mao, Bojun Liu, Chengli Song

Shanghai Institute for Minimally Invasive Therapy, School of Health Science and Engineering, University of Shanghai for Science and Technology, 200093, China.

Address correspondence to: Lin Mao, School of Health Science and Engineering, University of Shanghai for Science and Technology, No.516 Jungong Road, Yangpu District, Shanghai 200093, China. Tel: +86-21-55572159. E-mail: linmao@usst.edu.cn.

DOI: https://doi.org/10.61189/883654uegazz

Received March 21, 2024; Accepted June 5, 2024; Published September 30, 2024

Highlights

● A V-shaped vascular clamp featuring a locking mechanism and transverse teeth has been developed.

● Comparative analysis of clamps with various inner diameters reveals optimal closure with specific configurations.

● The designed clamp presents superior stress-strain response, robust clamping force, and consistent corrosion resistance.