CONTENTS IN BRIEF Pulmonary nodule intelligent agent: from auxiliary diagnostic tools to a new paradigm of intelligent agent medicine - also discussing the formation of the discipline system of intelligent agent medicine Progress and prospects of AI intelligent agents empowering the diagnosis and treatment of pulmonary nodules Respiratory internet of things-driven precision monitoring and closed-loop management: asthma care from ward to home The potential and prospects of AI empowering grassroots doctors in case analysis and reporting Intelligent agent empowers correction of pathologically overlooked early lung cancer cases in nodule reporting Digital humans, virtual experts, and patient education and management: a new model for respiratory health communication Metaverse medicine and innovation in respiratory education: from the classroom to immersive clinical training Current applications and development strategies of metaverse innovation models in otolaryngology clinical practice and education Design concept for a neurology metaverse teaching system based on the Fudan Zhongshan "huisheng intelligent education" platform